If you're in New England and interested in design, software and usability you'll want to check out the Mini-UPA one day conference. It's a one day event so you won't be tied up all week and it's jam packed with great speakers. There are over 30 speakers talking about all sorts of things from Web Apps, Interaction Techniques, Analytics, User Experience and design. Best of all the event is really affordable for a full day of speakers and classes. The event is May 28th so go put it on your calendar and sign-up now.
I'm on the board of UPA Boston and my company is also co-sponsoring the event but don't let that stop you from showing up. I hope to see you there.